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Megaloblastic Anemia

Megaloblastic Anemia

Hematology

Overview

Megaloblastic anemia is a group of disorders sharing similar abnormal blood cell morphology in the peripheral blood and bone marrow. It is commonly caused by vitamin B12 deficiency, folate deficiency, or defects in DNA synthesis.

Symptoms

  • Pallor
  • Fatigue
  • Glossitis
  • Loss of appetite
  • Numbness of the hands and feet

Treatment

Treatment centers on supplementing folate and vitamin B12 and correcting the underlying cause, with standardized supplementation and monitoring of blood count recovery under medical guidance.

Dietary advice

Eat plenty of foods rich in folate and vitamin B12, such as fresh leafy greens, animal liver, eggs, and dairy, and use appropriate cooking methods to minimize nutrient loss.

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