Myelofibrosis

Overview

Myelofibrosis is a myeloproliferative neoplasm originating from hematopoietic stem cells, characterized by fibrosis of the bone marrow. It commonly presents with anemia, splenomegaly, and constitutional symptoms.

Symptoms

• Fatigue
• Anemia
• Splenomegaly
• Night sweats
• Weight loss

Treatment

Treatment centers on symptomatic support and improving anemia and splenomegaly symptoms; targeted drug therapy may be used, and eligible patients may be considered for hematopoietic stem cell transplantation, with specialist follow-up.

Dietary advice

Maintain balanced nutrition with easily digestible high-protein, high-vitamin foods, and eat small, frequent meals to reduce abdominal discomfort caused by splenomegaly.