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Cushing's Syndrome

Endocrinology

Overview

Cushing's syndrome is an endocrine disorder caused by prolonged exposure to excess cortisol. Clinical features may include hypertension, central obesity, purple striae, a rounded moon face, a dorsocervical fat pad, muscle weakness, and osteoporosis.

Symptoms

  • Central obesity
  • Moon face
  • Purple striae
  • Hypertension
  • Hirsutism
  • Fatigue

Treatment

Treatment targets the underlying cause; surgical removal is preferred for pituitary or adrenal tumors, sometimes with adjuvant radiotherapy or medication. Cases caused by long-term glucocorticoid use require gradual dose adjustment under medical guidance.

Dietary advice

Follow a low-salt, low-sugar, low-fat, high-protein diet and control total calories to reduce obesity and elevated blood sugar. Supplement calcium and potassium, and limit high-salt foods.

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